Anti-CD114 / G-CSFR Monoclonal Antibody (Clone:LMM741) APC Conjugated

Product code: 30-1076-AC

Clone name : LMM741
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : APC

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100 Tests

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For estimated delivery dates, please contact us at [email protected]

Format : Purified
Amount : 100 Tests
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Content : Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CSF3R
Gene ID : 1441
Uniprot ID : Q99062
Alternative Name : CSF3R, GCSFR
Immunogen Information : CHO cells transfected with human CD114

CD114 / G-CSFR (granulocyte colony-stimulating factor receptor, also known as CSF3R) is a type I transmembrane glycoprotein which upon binding of its ligand (G-CSF, granulocyte colony-stimulating factor) homodimerizes and activates signaling transduction to mediate cell proliferation, survival, and differentiation. It is expressed by granulocytes at all stages of their differentiation, as well as by monocytes, dendritic cells, and mature platelets. Among non-hematopoietic cells, it is expressed e.g. by endothelial cells, placenta, trophoblasts, and many tumor cell lines. This antigen is a target for stem cell mobilization for blood stem cell transplantation, for enhancing recovery of myelopoiesis following chemotherapy and in the treatment of patients with severe chronic neutropenia.

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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