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    7. Anti-CD11b activation epitope Monoclonal Antibody (Clone:CBRM1/5)-PE Conjugated

    Anti-CD11b activation epitope Monoclonal Antibody (Clone:CBRM1/5)-PE Conjugated

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    Figure 1: Surface staining of PMA-activated human peripheral blood cells with anti-human CD11b activation epitope (CBRM1/5) PE.

    Anti-CD11b activation epitope Monoclonal Antibody (Clone:CBRM1/5)-PE Conjugated

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    Product code: 30-2141

    Clone name : CBRM1/5
    Clonality : Monoclonal
    Application : FACS
    Reactivity : Human
    Conjugate : PE

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    100 tests
    $418.00 

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    • Product Info
    • Antigen Details
    • Description
    • Application Note
    • Review   (0)
    Amount : 100 tests
    Isotype : Mouse IgG1
    Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
    Immunogen Information : Information not available

    CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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    Anti-CD11b activation epitope Monoclonal Antibody (Clone:CBRM1/5)-PE Conjugated

    Product code: 30-2141
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