Anti-CD195 / CCR5 Monoclonal Antibody (Clone:T21/8) Biotin Conjugated

Product code: 30-1509-B

Clone name : T21/8
Clonality : Monoclonal
Application : ICC, FACS
Reactivity : Human
Conjugate : Biotin

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0.1 mg
$437.00 

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Amount : 0.1 mg
Isotype : Mouse IgG1 kappa
Purification : Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
Content : Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CCR5
Gene ID : 1234
Uniprot ID : P51681
Alternative Name : CCR5, CMKBR5
Immunogen Information : CCR5 peptide (Met1-Lys22) KLH conjugate

Specificity: The mouse monoclonal antibody T21/8 recognizes an extracellular epitope on the N-teminus of CD195, an approximately 45 kDa G-protein coupled receptor 1 family protein expressed on resting T cells, monocytes, macrophages, and immature dendritic cells.

Description: CD195 / CCR5 (also known as CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues), such as MIP-1 alpha, MIP-1 beta, or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype, monocytes, macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly, along with CD4, CD195 / CCR5 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.

Flow cytometry: Recommended dilution: 1-5 μg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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