Anti-CD325 PE Mab(8C11)

Product code: 30-2894

Clone name : 8C11
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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0.1 mg

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Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content : Formulation : Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Gene ID : 1000
Uniprot ID : P19022
Alternative Name : N-Cadherin, cadherin 2, CDHM, CDH2
Immunogen Information : Purified human IgE.

Specificity: The mouse monoclonal antibody 4H10 reacts with human IgE; it recognizes an epitope different from the ones recognized by BE5 and 4G7 antibodies to IgE. The epitope is located within the amino acids 267-279 (TWLEDGQVMDVDL).

Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.

Flow cytometry: Recommended dilution: 1-5 μg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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