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  7. Anti-CD7 (T-Cell Leukemia Marker) Monoclonal Antibody(Clone: B-F12)

Anti-CD7 (T-Cell Leukemia Marker) Monoclonal Antibody(Clone: B-F12)

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Fig. 1: SDS-PAGE Analysis Purified CD7 Mouse Monoclonal Antibody (Clone B-F12). Confirmation of Integrity and Purity of Antibody.

Anti-CD7 (T-Cell Leukemia Marker) Monoclonal Antibody(Clone: B-F12)

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Product code: 36-3505

Clone name : B-F12
Clonality : Monoclonal
Application : FACS, IF
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG2a, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : CD7
Gene ID : 924
Uniprot ID : P09564
Alternative Name : GP40; Leu9; p41; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
Immunogen Information : Chronic Lymphoid Leukemia cells (CLL)
Recognizes a protein of 40kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

Flow Cytometry (0.5-1µg/million cells); Immunofluorescence (0.5-1µg/ml); Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-CD7 (T-Cell Leukemia Marker) Monoclonal Antibody(Clone: B-F12)

Product code: 36-3505
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