Anti-HLA-Class I Monoclonal Antibody (Clone:MEM-123)
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| Gene : | HLA-A |
| Uniprot ID : | P01892 |
| Alternative Name : | HLA-A, HLAA |
| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG3 |
| Immunogen Information : | COS-7 African green monkey kidney cells |
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
Flow Cytometry Recommended dilution:4 µg/ml
Immunoprecipitation ELISA
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane |
| Post transnational modification: | Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity). |
| BioGrid: | 109360. 40 interactions. |
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