Anti-HLA-Class I Monoclonal Antibody (Clone:MEM-123)
|Amount :||0.1 mg|
|Isotype :||Mouse IgG3|
|Purification :||Purified by protein-A affinity chromatography|
|Storage condition :||Store at 2-8°C. Do not freeze.|
|Uniprot ID :||P01892|
|Alternative Name :||HLA-A, HLAA|
|Immunogen Information :||COS-7 African green monkey kidney cells|
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
Flow Cytometry Recommended dilution:4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Post transnational modification:||Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).|
|BioGrid:||109360. 40 interactions.|