Monoclonal Antibody to Mouse PD-1 (Clone: ABM5F42)
|Gene ID :||18566|
|Uniprot ID :||Q02242|
|Alternative Name :||Programmed cell death protein 1, Protein PD-1, CD279|
|Amount :||100 µg|
|Isotype :||Rat IgG2b, kappa|
|Immunogen Information :||partial length recombinant protein (a.a 07-211) of mPD-1 was used as the immunogen for this antibody.|
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
|Purification :||Protein G Chromatography|
|Content :||100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.|
|Storage condition :||Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.|
FACS: 0.5-1 µg/10^6
For Research Use Only. Not for use in diagnostic/therapeutics procedures.