Anti-HNF1A (Pancreatic Tumor Suppressor) Monoclonal Antibody(Clone: HNF1A/2087)

Name: Anti-HNF1A (Pancreatic Tumor Suppressor) Monoclonal Antibody(Clone: HNF1A/2087)
Brand: Abeomics
SKU: 36-3229
Price: 429.0000 USD
Availability: InStock
Rating: 4.5 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Pancreas stained with HNF1A Mouse Monoclonal Antibody (HNF1A/2087).

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Fig. 1: Formalin-fixed, paraffin-embedded human Pancreas stained with HNF1A Mouse Monoclonal Antibody (HNF1A/2087).

Fig. 2: Formalin-fixed, paraffin-embedded human Pancreas stained with HNF1A Mouse Monoclonal Antibody (HNF1A/2087).

Fig. 3: Formalin-fixed, paraffin-embedded human Small Intestine stained with HNF1A Mouse Monoclonal Antibody (HNF1A/2087).

Fig. 4: SDS-PAGE Analysis Purified HNF1A Mouse Monoclonal Antibody (HNF1A/2087). Confirmation of Integrity and Purity of Antibody.

Fig. 5: Analysis of Protein Array containing more than 19,000 full-length human proteins using HNF1A Mouse Monoclonal Antibody (HNF1A/2087). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3229

Clone name :	HNF1A/2087
Application :	ELISA, IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS


Gene :	HNF1A
Gene ID :	6927
Uniprot ID :	P20823
Alternative Name :	Albumin proximal factor; Hepatic nuclear factor 1 alpha; Hepatic transcription factor 1 alpha; HNF-1A; Interferon production regulator factor; LFB1; LFB1 hepatic nuclear factor; Liver specific transcription factor LFB1; Maturity onset diabetes of the young 3 (MODY3); TCF1; Transcription factor 1 hepatic
Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Immunogen Information :	Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary)

HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicatedHNF1Aas a susceptibility gene for pancreatic cancer.

Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

ELISA (For coating, order antibody without BSA);Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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