Anti-Human CD344 Antibody (Clone : CH3A4A7)

Product code: 30-2577

Clone name : CH3A4A7
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1 kappa
Purification : Purified by protein-A affinity chromatography
Content : 1 mg/ml
Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : FZD4
Gene ID : 8322
Alternative Name : Frizzled-4, FZD4, EVR1, FEVR, GPCR,frizzled class receptor 4
Immunogen Information : WERI-RB-1 retinoblastoma cells

CD344 (Frizzled class receptor 4) is a G-protein coupled 7-TM protein, predominantly expressed in fetal neuronal progenitor cells, neuronal intestinal cells, as well as in the kidney, lung, brain, and liver. CD344 is important for regulation of cell polarity, proliferation, and tissue development. Defects in CD344 expression, or its mutation, lead e.g. to serious failures in retinal vascularization, defects in cerebellum, progressive hearing loss, or impaired corpora lutea formation and function.
Specificity : The mouse monoclonal antibody CH3A4A7 recognizes an extracellular epitope of CD344 (Frizzled 4), a 7-TM protein of G-protein-coupled receptor family, which is a marker for neuronal stem cells.

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