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  7. Anti-Human CD42b APC (Clone : AK2)

Anti-Human CD42b APC (Clone : AK2)

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Figure 1 : Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD42b (AK2) APC antibody (10 µl reagent / 100 µl of peripheral whole blood).

Anti-Human CD42b APC (Clone : AK2)
Anti-Human CD42b APC (Clone : AK2)

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Figure 1 : Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD42b (AK2) APC antibody (10 µl reagent / 100 µl of peripheral whole blood).
Figure 2 : Separation of human CD45 negative CD42b positive thrombocytes (red-filled) from CD42b negative neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD42b (AK2) APC antibody (10 µl reagent / 100 µl of peripheral whole blood).

Product code: 30-2565

Clone name : AK2
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : APC

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100 tests
$443.00 

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  • Product Info
  • Antigen Details
  • Description
  • Application Note
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Amount : 100 tests
Isotype : Mouse IgG1
Purification : The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Content : Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : GP1BA
Gene ID : 2811
Alternative Name : BSS, GP1B, VWDP, CD42B, GPIbA, BDPLT1, BDPLT3, DBPLT3,glycoprotein Ib platelet subunit alpha
Immunogen Information : Human platelets
CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.
Specificity : The mouse monoclonal antibody AK2 recognizes an extracellular epitope of CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c; 160 kDa); CD42b/c forms a noncovalent complex with CD42a and CD42d.

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-Human CD42b APC (Clone : AK2)

Product code: 30-2565
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