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  7. Anti-MUC5AC Monoclonal Antibody (Clone:IHC625)

Anti-MUC5AC Monoclonal Antibody (Clone:IHC625)

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Figure 1: Immunohistochemical analysis of MUC5AC (Clone: IHC625) on Stomach Cancer

Anti-MUC5AC Monoclonal Antibody (Clone:IHC625)

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Product code: 44-1050

Clone name : IHC625
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •   0.1 ml

  •  0.5 ml

  • $282.00 

  • $469.00 

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG1
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : MUC5AC
Gene ID : 4586
Uniprot ID : P98088
Alternative Name : MUC5AC, MUC5
Immunogen Information : Recombinant Human MUC5AC

Mucin 5AC (MUC5AC) is a secretory-type mucin found in columnar mucous cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon, but not in normal colon cells. MUC5AC expression is indicated in carcinomas wherein the type is defined as diffuse and infiltrative, and those located mainly in the antrum. Studies have also suggested a correlation between MUC5AC and colorectal signet-ring cell carcinoma, with overexpression of MUC5AC relating to the carcinogenesis, malignant potential, progression, and clinical behaviors.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
Post transnational modification: Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide.
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Anti-MUC5AC Monoclonal Antibody (Clone:IHC625)

Product code: 44-1050
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