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    7. Anti-PD-1 Monoclonal Antibody (Clone:IHC001)

    Anti-PD-1 Monoclonal Antibody (Clone:IHC001)

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    Figure 1: Immunohistochemical analysis of PD-1 (Clone: IHC001) on Tonsil

    Anti-PD-1 Monoclonal Antibody (Clone:IHC001)

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    Product code: 44-1067

    Clone name : IHC001
    Clonality : Monoclonal
    Application : IHC
    Reactivity : Human

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    For estimated delivery dates, please contact us at support@abeomics.com

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    •   0.1 ml

    •  0.5 ml

    • $288.00 

    • $432.00  $345.60 

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    • Product Info
    • Antigen Details
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    Format : Purified
    Amount : 0.5 ml
    Isotype : Mouse IgG2b
    Purification : Protein A/G Chromatography
    Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
    Storage condition : Store at 2°C - 8°C. Do not freeze.
    Gene : PDCD1
    Gene ID : 5133
    Uniprot ID : Q15116
    Alternative Name : PDCD1, PD1
    Immunogen Information : Recombinant human His-PD1

    Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T-cell regulators, expressed as a co-receptor on the surface of activated T-cells, B-cells, and macrophages. New studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to anti-tumor immunity, as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6, PD-1 is expressed by fewer B cells and has therefore been considered a more specific marker for angioimmunoblastic T-cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer, including non–small-cell lung cancer, melanoma, and renal-cell cancer.

    Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Subcellular location: Membrane
    BioGrid: 111160. 61 interactions.
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    Anti-PD-1 Monoclonal Antibody (Clone:IHC001)

    Product code: 44-1067
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