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  7. Anti-pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) Monoclonal Antibody(Clone: rTFF1/1091)

Anti-pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) Monoclonal Antibody(Clone: rTFF1/1091)

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Fig. 1: Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with TFF1/pS2 Mouse Monoclonal Antibody (rTFF1/1091).

Anti-pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) Monoclonal Antibody(Clone: rTFF1/1091)
Anti-pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) Monoclonal Antibody(Clone: rTFF1/1091)

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Fig. 1: Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with TFF1/pS2 Mouse Monoclonal Antibody (rTFF1/1091).
Fig. 2: SDS-PAGE Analysis Purified TFF1/ps2 Mouse Monoclonal Antibody (rTFF1/1091). Confirmation of Purity and Integrity of Antibody.

Product code: 36-3232

Clone name : rTFF1/1091
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG1, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : TFF1
Gene ID : 7031
Uniprot ID : P04155
Alternative Name : BCEI, Breast Cancer Estrogen Inducible Protein, Gastrointestinal Trefoil Protein, Gastrointestinal trefoil protein pS2, HP1A, HPS2, pNR2, TFF1, Trefoil Factor 1
Immunogen Information : Recombinant full-length human TFF1 protein
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throµghout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thoµght to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.

Immunohistochemistry (Formalin-fixed. Not suitable for frozen tissues.) (0.5-1µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) Monoclonal Antibody(Clone: rTFF1/1091)

Product code: 36-3232
*specify in mg or ml

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