FITC Conjugated Anti-CD160 Monoclonal Antibody (Clone:BY55)

Product code: 30-1540F

Clone name : BY55
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : FITC

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100 tests

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Amount : 100 tests
Isotype : Mouse IgM kappa
Purification : Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content : Formulation : Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Storage condition : Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Gene : CD160
Gene ID : 11126
Uniprot ID : O95971
Alternative Name : NK1, NK28
Immunogen Information : Human NK cell line YT2C2

CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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