Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Immune-Check Point
        • Kits and Reagents
          • Luciferase reporter assay kits
          • Inhibitor Screening Kit
          • ELISA Kits
          • Molecular Biology Kits
          • Apoptosis Detection kits
          • Flowcytometry staining kits
          • Cell dissociation solutions
          • Western Blot membranes (Quick blots/ Q Blots)
        • Tissue Microarray
        • recmAb™
          • Recombinant Biosimilar Antibodies
          • Recombinant Rabbit Antibodies
          • Recombinant Mouse Antibodies
    • Pathways
        • All-Pathways

          View all pathways

        • interactive-pathways

          View all interactive pathways

    • Custom Service
      • Drug Discovery Screening Services
      • Stable Cell Line Development
      • Protein Production
      • Custom Antibody Development
    • Quick order
      • + Add More..

    • Support
    • Contact us
    • Distributors
    1. Catalog
    2. /
    3. Antibodies
    4. /
    5. Cell Signalling
    6. /
    7. Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb

    Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb

    Share:

    Fig-1: Flow cytometric analysis of Jurkat cells secondary antibody only negative control (blue) or treated with U0126 (red) or treated with PMA (green) using Phospho-ERK1/2 (Thr202/Tyr204) antibody ERK12T202Y204-A11.

    Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb
    Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb
    Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb
    Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb
    Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb
    Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb

    Roll over image to zoom in

       
    Fig-1: Flow cytometric analysis of Jurkat cells secondary antibody only negative control (blue) or treated with U0126 (red) or treated with PMA (green) using Phospho-ERK1/2 (Thr202/Tyr204) antibody ERK12T202Y204-A11.
    Fig 2 : Western blot analysis of Ramos cell extract untreated or treated with U0126 followed by no treatment or treatment with PMA using Phospho-ERK1/2 (Thr202/Tyr204) antibody ERK12T202Y204-A11.
    Fig-3: Western blot analysis of 293T cell extract treated with U0126  or TPA using Phospho-ERK1/2 (Thr202/Tyr204) antibody ERK12T202Y204-A11 at 0.1 µg/mL.
    Fig-4: ERK12T202Y204-A11 recognizes basal phosphorylation levels in mouse cells. Flow cytometric analysis of L929 cells  secondary antibody only (blue) or 0.1 µg/mL of isotype control (Cat# 12-4086) (orange) or of Phospho-ERK1/2 (Thr202/Tyr204) antibody ERK12T202Y204-A11 (green)
    Fig-5: Flow cytometric analysis of Jurkat cells, secondary antibody only negative control (blue), or treated with U0126 (red) or with PMA (green) using Phospho-Erk1/2 (T202/Y204) antibody ERK12T202Y204-A11 or Company C antibody at 0.43 µg/mL (manufacturer's recommended concentration).
    Fig-6: Western blot analysis of Ramos cells treated with U0126 or treated with TPA using 0.05 µg/mL of Phospho ERK1/2 (Thr202/Tyr204) antibody ERK12T202Y204-A11  or Company C antibody at recommended concentration of 0.34 µg/mL.

    Product code: 12-4005

    Clone name : ERK12T202Y204-A11
    Clonality : Monoclonal
    Application : FACS, WB
    Reactivity : Human
    Conjugate : Unconjugated

    Shipping Info:

    For estimated delivery dates, please contact us at support@abeomics.com

    Download TDS MSDS
    Write a review for this product on BioCompare
    Get $20 gift card from Amazon
    Size
    Price

    Available Pack Size(s)

    •   20 µl

    •  200 µl

    • $278.00 

    • $540.00  $432.00 

    Add to Wish List

    Bulk Order

    Shipping Info:

    For estimated delivery dates, please contact us at support@abeomics.com

    Download TDS MSDS

    • Product Info
    • Antigen Details
    • Description
    • Application Note
    • Review   (0)
    Format : Purified
    Amount : 200 µl
    Isotype : Rabbit IgG1k
    Content : 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
    Storage condition : Store at -20°C. Avoid repeated freeze and thaw cycles.
    Alternative Name : Mitogen-activated protein kinase 3, MAPK3, ERK2, p44-MAPK, PRKM3, Mitogen-activated protein kinase 1, MAPK1, ERK1, p42-MAPK, PRKM1, PRKM2
    Immunogen Information : A synthetic phospho-peptide corresponding to residues surrounding Thr202/Tyr204 of human phospho Erk1/2.

    Human Erk1 and Erk2 Ser/Thr kinases share 84% sequence identity and nearly all functions. These MAP kinases are activated in response to mitogens and growth factors as part of the Ras-Raf-MEK-ERK signal transduction cascade. This pathway regulates cell survival, differentiation, adhesion, cell cycle progression, and many other cellular processes. Upon phosphorylation, Erk1/2 translocate to the nucleus to activate transcription factors including c-Fos, Elk1, Ets1, and SP-1. There are more than 175 known cytoplasmic and nuclear substrates of Erk1/2. The Erk1/2 cascade is upregulated in many human cancers, even when oncogenic mutations are not found. Multiple small-molecule inhibitors of Erk1/2 have been developed, including ones targeting the ATP-binding site either competitively or irreversibly.

    1µg/mL - 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.(0.5mg/ml, more than 200 western blots)

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    There are currently no product reviews
    Write a review on this product!

    Customers who purchased this product also purchased

    Anti-gamma-tubulin Monoclonal Antibody (Clone:TU-32)

    Anti-gamma-tubulin Monoclonal ...

    details-Anti-gamma-tubulin Monoclonal Antibody (Clone:TU-32)
    Anti-SARS-CoV-2 Spike S2 antibody(DM25), Rabbit mAb

    Anti-SARS-CoV-2 Spike S2 antib...

    details-Anti-SARS-CoV-2 Spike S2 antibody(DM25), Rabbit mAb
    Anti-MDR3 Monoclonal Antibody (Clone:IHC621)

    Anti-MDR3 Monoclonal Antibody ...

    details-Anti-MDR3 Monoclonal Antibody (Clone:IHC621)
    Recombinant human NRG1 protein with C-terminal human Fc tag

    Recombinant human NRG1 protein...

    details-Recombinant human NRG1 protein with C-terminal human Fc tag
    Anti-Kappa Monoclonal Antibody (Clone:IHC610)

    Anti-Kappa Monoclonal Antibody...

    details-Anti-Kappa Monoclonal Antibody (Clone:IHC610)
    Monoclonal Antibody to Human TLR2 (Clone : TLR2.45)

    Monoclonal Antibody to Human T...

    details-Monoclonal Antibody to Human TLR2 (Clone : TLR2.45)
    Anti-Human CD257 (BAFF) (Tabalumab) – Fc Muted™

    Anti-Human CD257 (BAFF) (Tabal...

    details-Anti-Human CD257 (BAFF) (Tabalumab) – Fc Muted™
    Recombinant human VSIR protein with C-terminal human Fc tag

    Recombinant human VSIR protein...

    details-Recombinant human VSIR protein with C-terminal human Fc tag
    NALE™ Monoclonal Antibody to TLR9 (Clone: ABM1C51)

    NALE™ Monoclonal Antibody to...

    details-NALE™ Monoclonal Antibody to TLR9 (Clone: ABM1C51)
    Anti-Human IL 12/23 (Briakinumab)

    Anti-Human IL 12/23 (Briakinum...

    details-Anti-Human IL 12/23 (Briakinumab)
    MAPKAPK3 Recombinant Protein

    MAPKAPK3 Recombinant Protein

    details-MAPKAPK3 Recombinant Protein
    Anti-Human TCR Cbeta1 FITC (Clone : JOVI.1)

    Anti-Human TCR Cbeta1 FITC (Cl...

    details-Anti-Human TCR Cbeta1 FITC (Clone : JOVI.1)
    Mouse Monoclonal Antibody to IL-8 (Clone : 2D11C10)(Discontinued)

    Mouse Monoclonal Antibody to I...

    details-Mouse Monoclonal Antibody to IL-8 (Clone : 2D11C10)(Discontinued)
    Anti-Human HER-2 (Trastuzumab) – Biotin

    Anti-Human HER-2 (Trastuzumab)...

    details-Anti-Human HER-2 (Trastuzumab) – Biotin

    Most viewed Products

    Recombinant Human Thioredoxin-Like 4A

    Recombinant Human Thioredoxin-Like ...

    details-Recombinant Human Thioredoxin-Like 4A
    Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

    Monoclonal Antibody to Human IL-1be...

    details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
    NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

    NF-kB Leeporter™ Luciferase Repor...

    details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
    Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

    Monoclonal antibody to Human PD-L1 ...

    details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
    Polyclonal Antibody to Beta actin

    Polyclonal Antibody to Beta actin

    details-Polyclonal Antibody to Beta actin
    Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

    Monoclonal Antibody to Caspase-3 (P...

    details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
    Monoclonal Antibody to GAPDH (Clone: ABM22C5)

    Monoclonal Antibody to GAPDH (Clone...

    details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
    Monoclonal antibody to B7-H4 (Clone: ABM53A6)

    Monoclonal antibody to B7-H4 (Clone...

    details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
    Polyclonal Antibody to Beta Tubulin

    Polyclonal Antibody to Beta Tubulin

    details-Polyclonal Antibody to Beta Tubulin
    Peroxidase conjugated Goat anti Mouse IgG (H+L)

    Peroxidase conjugated Goat anti Mou...

    details-Peroxidase conjugated Goat anti Mouse IgG (H+L)

    Related Products

    Anti-GPRC5D antibody(DM62), Rabbit mAb

    Anti-GPRC5D antibody(DM62), Rabbit mAb

    Mouse Monoclonal Antibody to MIPEP (Clone: 166CT22.3.7)(Discontinued)

    Mouse Monoclonal Antibody to MIPEP (Clone: 166CT22.3.7)(Discontinued)

    Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb SureLight488 conjugate

    Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb SureLight488 conjugate

    close

    Please Login to write a Review !!


    close

    Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Clone: A11) rabbit mAb

    Product code: 12-4005
    *specify in mg or ml

    Abeomics Logo

    Antibodies & Engineered Cell Lines™

    Tel : 858-263-4982

    Fax : 858-247-7052

    Email : support@abeomics.com

    Connect with Us

    • Facebook
    • Twitter
    • Linkedin
    • YouTube

    Products

    • Antibodies
    • Cell Lines
    • Ligands and Inhibitors
    • Recombinant Proteins
    • Immune-Check Point
    • Kits and Reagents
    • Tissue Microarray
    • recmAb™

    Services

    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development

    Quick order

    + Add More..

    Newsletter

    Posters and Flyers

    © 2022 Abeomics. All rights reserved.
    • Blog
    • Sitemap
    • Terms
    • Privacy Policy
    • Legal
    • Email unsubscribe

    Item added to cart successfully

    No cart item available
    Continue shopping View Cart