Polyclonal Antibody to Anti-ATF6 Antibody(Discontinued)
|Amount :||100 μg/vial|
|Isotype :||Rabbit IgG|
|Purification :||Immunogen affinity purified.|
|Content :||Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/ml.|
|Storage condition :||At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.|
|Gene ID :||22926|
|Uniprot ID :||P18850|
|Alternative Name :||Cyclic AMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 alpha; Activating transcription factor 6 alpha; ATF6-alpha|
|Immunogen Information :||A synthetic peptide corresponding to a sequence at the C-terminus of human ATF6(599-614aa NINENVINGQDYEVMM), different from the related mouse and rat sequences by one amino acid.|
ATF6, a member of the leucine zipper protein family, is an endoplasmic reticulum(ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules. ATF6 gene is mapped to chromosome 1q23.3. ATF6 can constitutively induce the promoter of glucose-regulated protein(grp) genes through activation of the endoplasmic reticulum(ER) stress element(ERSE).
Western blot : 0.1-0.5μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Post transnational modification:||Phosphorylated in vitro by MAPK14/P38MAPK.|
|BioGrid:||116586. 48 interactions.|