Recombinant Human CD79B (C-His)
|Amount :||50 µg|
|Content :||Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4|
|AA sequence :||Recombinant Human CD79B is produced by our Mammalian expression system and the target gene encoding Ala29-Asp159 is expressed with a 6His tag at the C-terminus.|
|Alternative Name :||B-Cell Antigen Receptor Complex-Associated Protein Beta Chain; B-Cell-Specific Glycoprotein B29; Ig-Beta; Immunoglobulin-Associated B29 Protein; CD79b; CD79B; B29; IGB|
B-cell antigen receptor complex-associated protein beta chain (CD79B) is a single-pass type I membrane protein containing one Ig-like V-type (immunoglobulin-like) domain and one ITAM domain. CD79B is expressed on B cells and can form a covalent heterodimer with CD79A. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex.CD79B facilitates the phosphorylation of CD79A by recruiting kinases which phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.