Anti-Cytokeratin 18 Monoclonal Antibody (Clone:DC-10)-Biotin Conjugated
Figure-1: Flow cytometry analysis (intracellular staining) of HeLa cells with anti-human cytokeratin 18 (DC-10) biotin antibody (red, concentration in sample 6 μg/ml) streptavidin-APC, with blank sample (black).
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| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store at 2-8°C. Do not freeze. |
Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.Cytokeratin 18 belongs to type I family (acidic cytokeratins).
Flow cytometry: Recommended dilution: 2-6 μg/ml. Intracellular staining.
Western blotting: Recommended dilution: 1-2 μg/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus |
| Post transnational modification: | O-GlcNAcylation increases solubility, and decreases stability by inducing proteasomal degradation. |
| Tissue Specificity: | Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. |
| BioGrid: | 110073. 113 interactions. |
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