Anti-GLUT-1 (Tumor Progression and Mesothelioma Marker) Monoclonal Antibody(Clone: GLUT1/3132R)
Fig. 1: Formalin-fixed, paraffin-embedded human Tongue stained with GLUT-1 Recombinant Rabbit Monoclonal Antibody (GLUT1/3132R).
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| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | SLC2A1 |
| Gene ID : | 6513 |
| Uniprot ID : | P11166 |
| Alternative Name : | Erythrocyte/hepatoma glucose transporter; Glucose transporter type-1; GLUT1; GLUT1DS; GLUTB; GT1; GTG1; Gtg3; HepG2 glucose transporter; PED; RATGTG1; Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) |
| Immunogen Information : | Recombinant fragment of human GLUT1 protein (around aa 203-305) (exact sequence is proprietary) |
Recognizes a protein of 55kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).
ELISA (For coating use Ab at 1-2µg/ml order Ab without BSA); Flow Cytometry (1-2µg/million cells);Immunohistochemistry (Formalin-fixed) (0.5-1µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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