Anti-Podoplanin Monoclonal Antibody (Clone:IHC650)-Ready to Use

Product code: 44-1079

Clone name : IHC650
Clonality : Monoclonal
Application : IHC
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon
7 ml

Add to Wish List

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Amount : 7 ml
Isotype : Mouse IgG2a, kappa
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : PDPN
Gene ID : 10630
Uniprot ID : Q86YL7
Alternative Name : PDPN, GP36, PSEC0003, PSEC0025
Immunogen Information : Recombinant Human Podoplanin

"Podoplanin is a transmembrane mucoprotein specifically expressed in the endothelium of lymphatic capillaries, while remaining absent from the blood vasculature. The protein is co-localized with VEGFR3/FLT4 in normal skin and kidney. Anti-Podoplanin is useful in the identification of lymphangiomas, Kaposi’s sarcomas, epithelioid mesotheliomas, hemangioblastomas, seminomas, and some angiosarcomas which likely have lymphatic differentiation."

This product is available in ready to use format, hence no dilution is required.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: Cleaved by a metalloprotease within its extracellular (EC) domain, generating a membrane-bound C-terminal fragment (PCTF33) and an extracellular fragment. The resulting membrane-bound C-terminal fragment (PCTF33) is further processed between Val-150 and Val-151 by PSEN1/gamma-secretase generating the intracellular domain of podoplanin (PICD).
Tissue Specificity: Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas.
BioGrid: 115874. 4 interactions.
There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products