Anti-Thyroglobulin Monoclonal Antibody (Clone:IHC674)
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|Amount :||0.5 ml|
|Isotype :||Mouse IgG1|
|Purification :||Protein A/G Chromatography|
|Content :||Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide|
|Storage condition :||Store at 2°C - 8°C. Do not freeze.|
Thyroglobulin is a precursor to the thyroid hormones T4 and T3 and is present in the thyroid follicular cells. Nearly all thyroid follicular carcinomas stain for thyroglobulin and sometimes produce a focal staining pattern. Conversely, poorly differentiated carcinomas and non-thyroid adenocarcinomas do not stain for thyroglobulin. A panel of Anti-Thyroglobulin and Anti-Calcitonin is useful for identifying medullary thyroid carcinomas, whereas a panel of Anti-Thyroglobulin and Anti-TTF1 is useful for distinguishing between primary thyroid and lung neoplasms.
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Post transnational modification:||Sulfated tyrosines are desulfated during iodination.|
|Tissue Specificity:||Thyroid gland specific.|
|BioGrid:||112896. 3 interactions.|
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