G alpha 15 Stable Cell Line-MC2-CHO-K1-Human
Figure 1: Functional analysis of MC2 receptor.
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| Amount : | 2 vials |
| Content : | Each Vial contains cells in 45% culture medium, 45% FBS, 10% DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
| Alternative Name : | Human Recombinant MC2 Melanocortin Receptor Stable Cell Line |
The melanocortin receptor 2, MC2 receptor, is Gs-coupled GPCRs expressed in zona fasciculata of the adrenal cortex placental and stimulates production of cortisol. MC2 is a member of the rhodopsin family of 7-transmembrane and it's also known as the ACTH receptor or corticotropin receptor because it is specific for ACTH alone. Activation of the MC2 receptor initiates a cascade of events affecting multiple steps in corticoid steroidogenesis. Mutations in MC2 may result in familial glucocorticoid deficiency, a group of autosomal recessive disorders characterized by resistance to ACTH.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting and analyzing receptors. Culture Medium: Ham's F12, 10% FBS, 200 µg/ml Zeocin, 100 µg/ml Hygromycin B
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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