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  7. Monoclonal Antibody to Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16(Clone : CDH16/1071)

Monoclonal Antibody to Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16(Clone : CDH16/1071)

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Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with KSP-Cadherin Monoclonal Antibody (CDH16/1071)

Monoclonal Antibody to Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16(Clone : CDH16/1071)
Monoclonal Antibody to Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16(Clone : CDH16/1071)

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Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with KSP-Cadherin Monoclonal Antibody (CDH16/1071)
Formalin-fixed, paraffin-embedded Rat Kidney stained with KSP-Cadherin Monoclonal Antibody (CDH16/1071)

Product code: 36-1001

Clone name : CDH16/1071
Clonality : Monoclonal
Application : IHC, FACS, IF
Reactivity : Human, Rat

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100 µg
$459.00 

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  • Product Info
  • Antigen Details
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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1 Kappa
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : CDH16
Gene ID : 1014
Uniprot ID : O75309
Alternative Name : CDH16, UNQ695/PRO1340
Immunogen Information : Recombinant human CDH16 protein

This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Flow Cytometry (0.5-1µg/million cells in 0.1ml); Immunofluorescence (1-2µg/ml); Immunohistology (Formalin-fixed) (0.5-1µg/ml for 30 minutes at RT); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Tissue Specificity: Kidney specific.
BioGrid: 107449. 3 interactions.
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Monoclonal Antibody to Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16(Clone : CDH16/1071)

Product code: 36-1001
*specify in mg or ml

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