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    7. Monoclonal Antibody to RIG-I (Clone: ABM4H29)

    Monoclonal Antibody to RIG-I (Clone: ABM4H29)

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    Fig-1: Western blot analysis of RIG1/DDx58. Anti-RIG1/DDx58 antibody (Clone: ABM4H29) was tested at 2 µg/ml on human kidney lysate.

    Monoclonal Antibody to RIG-I (Clone: ABM4H29)
    Monoclonal Antibody to RIG-I (Clone: ABM4H29)
    Monoclonal Antibody to RIG-I (Clone: ABM4H29)
    Monoclonal Antibody to RIG-I (Clone: ABM4H29)

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    Fig-1: Western blot analysis of RIG1/DDx58. Anti-RIG1/DDx58 antibody (Clone: ABM4H29) was tested at 2 µg/ml on human kidney lysate.
    Fig-2: Immunohistochemical analysis of RIG1/DDx58 in human Colon Tissue using RIG1/DDx58 antibody (Clone: ABM4H29) at 15 µg/ml.
    Fig-3: Immunohistochemical analysis of RIG1/DDx58 in human Spleen Tissue using RIG1/DDx58 antibody (Clone: ABM4H29) at 15 µg/ml.
    Figure-4: Intracellular flow cytometric analysis of RIG-I in K562 Cell line using 0.5 µg/10^6 cells of Anti-RIGI antibody (ABM4H29). Green represent isotype control and red represent Anti-RIG I antibody (10-4121 Abeomics). Goat anti-mouse PE conjugate was used as secondary.

    Product code: 10-4121

    Clone name : ABM4H29
    Clonality : Monoclonal
    Application : IHC, FACS, WB
    Reactivity : Human

    Shipping Info:

    Order now and get it on Tuesday June 28, 2022

    Same day delivery FREE on San Diego area orders placed by 1.00 PM

    Local delivery areas

    Same-day delivery in San Diego available for the following zip codes:

    92121, 92122, 92037, 92117, 92109, 92110, 92101, 92010, 92011, 92009, 92008
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    Available Pack Size(s)

    •   25 µg

    •  100 µg

    • $100.00 

    • $280.00  $224.00 

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    Shipping Info:

    Order now and get it on Tuesday June 28, 2022

    Same day delivery FREE on San Diego area orders placed by 1.00 PM

    Download TDS MSDS

    • Product Info
    • Antigen Details
    • Description
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    Format : Purified
    Amount : 100 µg
    Isotype : Mouse IgG1 Kappa
    Purification : Protein G Chromatography
    Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
    Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
    Gene : DDX58
    Gene ID : 23586
    Uniprot ID : O95786
    Alternative Name : DDX58
    Immunogen Information : A partial length recombinant human RIG-I protein (amino acids 1-220) was used as the immunogen for this antibody.

    RIG-I (retinoic-acid-inducible gene I), also known as DDX58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58) is a 925-residue cytoplasmic viral RNA receptor, critically involved in the activation of the innate immune response to RNA virus infection. It is a member of the RIG-I-like receptor (RLR) family and is an essential intracellular sensor for several 5-triphosphorylated RNA viruses. RIG-I elicits its antiviral interferon (IFN) responses by recognizing viral double-stranded RNAs (dsRNAs). Structurally it comprises a helicase domain, a C-terminal domain, and N-terminal CARDs (caspase activation recruitment domains) involved in activating MAVS (mitochondrial antiviral signaling protein). Upon binding of 5'-triphosphorylated RNA, RIG-I undergoes conformational changes and post-translational modifications that allow multimerization and interaction with the mitochondrial antiviral signaling protein (MAVS).

    Western blot analysis: 2-4 µg/ml, Immunohistochemical analysis: 15 µg/ml,  Flowcytometric analysis: 0.5-1µg/10^6 cells

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Subcellular location: Cytoplasm, Cell projection, Cytoplasm, Cell junction
    Post transnational modification: Sumoylated, probably by MUL1; inhibiting its polyubiquitination.
    Tissue Specificity: Present in vascular smooth cells (at protein level).
    BioGrid: 117121. 43 interactions.
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    Monoclonal Antibody to RIG-I (Clone: ABM4H29)

    Product code: 10-4121
    *specify in mg or ml

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