Mouse Monoclonal Antibody to Androgen Receptor(Clone: AR 441)(Discontinued)
|Amount :||0.5 ml|
|Isotype :||Mouse IgG1|
|Content :||This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.|
|Storage condition :||Store at 2-8°C.|
This antibody is specific to a protein of 110 kDa, identified as androgen receptor. This antibody reacts with full length AR and also with the newly described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors.
IHC : 1:25-1:50
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Subcellular location:||Nucleus, Cytoplasm|
|Post transnational modification:||Palmitoylated by ZDHHC7 and ZDHHC21. Palmitoylation is required for plasma membrane targeting and for rapid intracellular signaling via ERK and AKT kinases and cAMP generation.|
|Tissue Specificity:||Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107).|
|BioGrid:||106862. 284 interactions.|