Mouse Monoclonal Antibody to Human PRTN3 (Clone : 11F1A5)(Discontinued)
|Amount :||40 µg|
|Isotype :||Mouse IgG2b,Kappa|
|Purification :||Protein A chromatography|
|Content :||0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.|
|Storage condition :||The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.|
|Gene ID :||5657|
|Uniprot ID :||P24158|
|Alternative Name :||ACPA, AGP7, azurophil granule protein 7, C-ANCA, C-ANCA antigen, CANCA, Leukocyte proteinase 3, MBN, MBT, Myeloblastin, Neutrophil proteinase 4, NP-4, NP4, P29, PR-3, PR3, serine proteinase, neutrophil, Wegener autoantigen, Wegener granulomatosis autoantigen|
|Immunogen Information :||Recombinant Human PRTN3|
PRTN3 (Proteinase 3) is a protein coding gene that belongs to the peptidase S1 family, Elastase subfamily. PRTN3 contains a 1 peptidase S1 domain. Among its related pathways are immune system and cytokine signaling in the immune system. PRTN3 degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Diseases associated with PRTN3 include Wegener Granulomatosis and Rapidly Progressive Glomerulonephritis.
ELISA detection: 0.01-0.1 µg/ml
Western blot: 1-2 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.