Polyclonal Antibody to Beta Tubulin
Figure-1: Western blot analysis of Beta Tubulin. Anti- Beta Tubulin antibody (11-13002) was used at 4 µg/ml on 1) A431, 2) Hela, 3) MCF7 and 4) 3T3 lysates.
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Tubulin is one of several members of a small family of globular proteins and is the major constituent of microtubules. The most common members of the tubulin family are alpha-tubulin and beta-tubulin. It appears to play an important role in the formation of platelet. It is involved in the pathogenesis of Cortical dysplasia, complex, with other brain malformations 6 (CDCBM6) and distal hereditary motor neuropathy, type 2. Ubiquitously expressed with highest levels in spleen, thymus and immature brain. It is expressed exclusively in megakaryocytes and platelets in humans.
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Western blot analysis: 4-6 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm |
| Post transnational modification: | Phosphorylated on Ser-172 by CDK1 during the cell cycle, from metaphase to telophase, but not in interphase. This phosphorylation inhibits tubulin incorporation into microtubules. |
| Tissue Specificity: | High expression in brain, where it represents 30% of all beta-tubulins. |
| BioGrid: | 113131. 128 interactions. |
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