Polyclonal Antibody to EGFR (Ab-869)
|Amount :||100 µg|
|Isotype :||Rabbit IgG|
|Content :||Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Storage condition :||Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.|
Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor.
Predicted MW: 175kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Post transnational modification:||Methylated. Methylation at Arg-1199 by PRMT5 stimulates phosphorylation at Tyr-1197.|
|Tissue Specificity:||Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.|
|BioGrid:||108276. 1217 interactions.|