Recombinant human CEACAM5 protein with C-terminal 6×His tag
|The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
|Storage condition :
|Store at -80°C for 12 months (Avoid repeated freezing and thawing)
|Alternative Name :
|CEACAM-5,CD66e,CEA,Meconium antigen 100
The protein has a predicted molecular mass of 72.2 kDa after removal of the signal peptide. The apparent molecular mass of CEACAM5-His is approximately 100-130 kDa due to glycosylation.
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.