Recombinant Mouse IL-13RA1/NR4/CD213a1(C-Fc)
|Amount :||50 µg|
|Content :||Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.|
|AA sequence :||Recombinant Mouse Interleukin-13 receptor subunit alpha-1 is produced by our Mammalian expression system and the target gene encoding Ala25-Thr340 is expressed with a Fc tag at the C-terminus.|
|Alternative Name :||Interleukin-13 receptor subunit alpha-1;IL-13RA1;Interleukin-13-binding protein;Novel cytokine receptor 4;NR4;CD213a1|
Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TRAF3IP1 and binds with low affinity to interleukin-13(IL3). IL-13RA1, together with IL4RA, can form a functional receptor for IL13. It also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. The WSXWS motif in domains appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.