VISTA Stable Cell Line-CHO-K1-Human(Currently Unavailable)
Figure 1: FACS analysis of VISTA expression in CHO-K1/VISTA cells.
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| Amount : | 2 vials |
| Content : | Each Vial contains cells in 95% complete growth medium+ 5% DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
V-domain Ig suppressor of T cell activation (VISTA) is a potent negative regulator of T-cell function that is expressed on hematopoietic cells. VISTA levels are heightened within the tumor microenvironment, in which its blockade can enhance antitumor immune responses in mice. In humans, blockade of the related programmed cell death 1 (PD-1) pathway has shown great potential in clinical immunotherapy trials. Here, we report the structure of human VISTA and examine its function in lymphocyte negative regulation in cancer.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting. Culture Medium: F12K, 10% FBS, 600 µg/ml G418
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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