Anti-BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma) Monoclonal Antibody(Clone: BARX1/2760)
|Amount :||100 µg|
|Isotype :||Mouse IgG, kappa|
|Content :||200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.|
|Storage condition :||Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.|
|Uniprot ID :||Q9HU1|
|Alternative Name :||BarH like homeobox 1; BarX 1; BARX homeobox 1; Homeobox protein BarH like 1|
|Immunogen Information :||Recombinant full-length human BARX1 protein.|
BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog sµggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes HCC migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC.
Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.