Polyclonal Antibody to MyoD (Ab-200)
Figure 1: Western blot analysis of extracts from Hela cells using MyoD (Ab-200) Antibody 35-1473 and the same antibody preincubated with blocking peptide.
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
MyoD encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the
myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for
myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.
Predicted MW: 40kd, Western blotting: 1:500~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Post transnational modification: | Methylation at Lys-104 by EHMT2/G9a inhibits myogenic activity. |
| BioGrid: | 110737. 69 interactions. |
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