Recombinant human CD70 protein with C-terminal human Fc and 6×His tag
|The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
|Storage condition :
|Store at -80°C for 12 months (Avoid repeated freezing and thawing)
|Alternative Name :
The protein has a predicted molecular mass of 44.1 kDa after removal of the signal peptide.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.